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These medications prevent the reabsorption of sodium and water in a specific part of the nephron called the distal convoluted tubule.

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The difference between this medicine and prior ones seems to be the diuretic.

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However, these studies were confounded by the benefits of ACE-inhibitor therapy on the rate of disease progression.

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Turns out that diuretics (Chlorothiazide in this case) are a known factor in causing Impotence in a high percentage of males.

Reduced aldosterone secretion by quinapril may result in a small increase in serum potassium.

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Tolerated 5mg for 5 years with little side effects.

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